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  5. Tocris Bioscience™ KRIBB11

Tocris Bioscience™ KRIBB11

Catalog No. 548050
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548010 10 mg
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Catalog No. 548050 Supplier Tocris Bioscience™ Supplier No. 5480/50
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Description

HSF1 inhibitor

KRIBB11 is a heat shock factor (HSF) inhibitor (IC50 = 1.2 μM). Increases apoptosis in cancer cells treated with the HSP90 inhibitors Geldanamycin (Cat. No. 1368) and 17-AAG (Cat. No. 1515). Blocks downstream induction of HSP27 and HSP70. Inhibits tumor growth in vivo.

Specifications

Chemical Name or Material KRIBB11
CAS 342639-96-7
Synonym N2-1H-Indazol-5-yl-N6-methyl-3-nitro-2,6-pyridinediamine
Quantity 50 mg
Solubility Soluble to 100mM in DMSO
Molecular Formula C13H12N6O2
Formula Weight 284.27
Physical Form Solid
Product Type Bioactive Small Molecule
Purity >99%

Research Use Only. Not For Human or Veterinary Use

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