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R&D Systems™ Mca-KPLGL-Dpa-AR-NH2 Fluorogenic Peptide Substrate

Catalog No. ES010
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1 mg
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ES010 1 mg
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Description

Substrate for MMP-1, MMP-2, MMP-7, MMP-8, MMP-9, MMP-12, MMP-13, MMP-14, MMP-15, MMP-16, ADAM10, ADAM17/TACE, Cathepsin D, and Cathepsin E

  • The peptide substrate contains a highly fluorescent 7-methoxycoumarin group that is efficiently quenched by resonance energy transfer to the 2,4-dinitrophenyl group
  • Can be used to measure the activities of peptidases capable of cleaving an amide bond between the fluorescent group and the quencher group, causing an increase in fluorescence
  • Purity >95% by HPLC
  • The cleavage site is the peptide bond between Gly and Leu

Specifications

Quantity 1 mg
Product Type Mca-Lys-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2
Storage Requirements Samples are stable for up to twelve months from date of receipt at -20° C to -70° C. The substrate can be aliquoted and stored -20° C to -70° C in a manual defrost freezer for six months. Avoid repeated freeze-thaw cycles. Protect from exposure to direct light.
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