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Tocris Bioscience™ MK6-83
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Catalog No. 554750
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Catalog No. 554750 Supplier Tocris Bioscience™ Supplier No. 5547/50
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Description

TRPML channel activator

MK6-83 is a TRPML channel activator (EC50 = 110 nM). Also activates F408Δ and F465L TRPML mutants (EC50 values are 0.1 and 1.23 μM respectively). Restores endolysosomal trafficking and zinc homeostasis in lysosomes of mucolipidosis type IV (MLIV) mutant fibroblasts.

Specifications

Chemical Name or Material MK6-83
CAS 1062271-24-2
Synonym 5-Methyl-N-[2-(1-piperidinyl)phenyl]-2-thiophenesulfonamide
Quantity 50 mg
Solubility Soluble to 100mM in DMSO and to 20mM in ethanol
Molecular Formula C16H20N2O2S2
Formula Weight 336.47
Physical Form Solid
Product Type Bioactive Small Molecule
Purity >98%

Research Use Only. Not For Human or Veterinary Use

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