DescriptionTRPML channel activator (EC50 = 110 nM). Also activates F408Δ and F465L TRPML mutants (EC50 values are 0.1 and 1.23 μM respectively). Restores endolysosomal trafficking and zinc homeostasis in lysosomes of mucolipidosis type IV (MLIV) mutant fibroblasts.
|Bioactive Small Molecule|
Safety and Handling
Recommended Storage : Store at 4°C
Research Use Only. Not For Human or Veterinary Use
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