R&D Systems™ Recombinant Mouse LAG-3 Fc Chimera Protein, CF

Catalog No.	Quantity
3328L3050	50 μg

Catalog No. 3328L3050 Supplier R&D Systems™ Supplier No. 3328L3050

Description

Extensive quality control produces industry leading bioactivity and lot-to-lot consistency that instills confidence in results and ensures reproducibility. Applications: Bioactivity

Measured by its ability to induce TNF-alpha secretion by JAWSII mouse immature dendritic cells. The ED50 for this effect is 0.4-2.4 μg/mL.

Specifications

• Accession Number: Q61790
• For Use With (Application): Bioactivity
• Formulation: Lyophilized from a 0.2 μm filtered solution in PBS.
• Gene ID (Entrez): 3902
• Molecular Weight (g/mol): M.W. (Observed): 85-100 kDa, reducing conditions; M.W. (theoretical): 72.4 kDa (monomer)
• Name: LAG-3 Fc Chimera
• Quantity: 50 μg
• Source: Mouse myeloma cell line, NS0-derived mouse LAG-3 protein Mouse LAG-3 (Gly24-Leu442) (N-terminus) Accession # Q61790 IEGRMDP Mouse IgG2A (Glu98-Lys330) (C-terminus)
• Storage Requirements: 12 months from date of receipt, <= -20 °C as supplied. 1 month, 2°C to 8°C under sterile conditions after reconstitution. 3 months, <= -20 °C under sterile conditions after reconstitution.
• Structural Form: Disulfide-linked homodimer
• Endotoxin Concentration: <0.10 EU / 1 μg of the protein by the LAL method.
• Gene Symbol: Lag3
• Conjugate: Unconjugated
• Recombinant: Recombinant
• Reconstitution: Reconstitute at 250 μg/mL in PBS. Reconstitute 30 minutes prior to use with minimal agitation.
• Purity or Quality Grade: >95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie™ Blue Staining.
• Protein: LAG-3