R&D Systems QAQ Dichloride, Tocris™

Photoswitchable Nav, Cav and Kv channel blocker

Manufacturer: R&D Systems 5470/50

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Catalog No. 547050

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Research Use Only. Not For Human or Veterinary Use


    Chemical Name or Material QAQ dichloride
    Assay Percent Range >98%
    Molecular Formula C28H44Cl2N6O2
    Formula Weight 567.59
    Synonym 2,2'-[1,2-Diazenediylbis(4,1-phenyleneimino)bis[N,N,N-triethyl-2-oxo-ethanaminium] dichloride
    Recommended Storage Store at -20°C.
    Quantity 50mg
    Solubility Soluble to 50mM in water
    Physical Form Solid
    Product Type Bioactive Small Molecules

    • Blocks channels in the trans conformation
    • Switches conformation from cis to trans at 500nm and trans to cis at 380nm
    • Normally membrane impermeant, but enters nociceptive neurons via ion channels activated by noxious stimuli, particularly TRPV1
    • Exhibits optically reversible local anesthesia in rats

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