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Invitrogen™ RAB11B Polyclonal Antibody
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Catalog No. PIPA531348
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PIPA531348 100 μL
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Catalog No. PIPA531348 Supplier Invitrogen™ Supplier No. PA531348
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Description

Rabbit Polyclonal Antibody

Recommended positive controls: U87-MG, SK-N-SH, IMR32, SK-N-AS, Mouse brain, PC-12, Rat2. Predicted reactivity: Mouse (100%), Rat (100%), Pig (100%), Chicken (99%), Rhesus Monkey (100%), Bovine (100%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Rab proteins are low-molecular-weight GTP-binding proteins that form the largest branch of the Ras superfamily of GTPases. Located on the cytoplasmic face of organelles and vesicles, rab proteins are involved in intracellular membrane fusion reactions. Three membrane proteins, synaptosomal associated protein of 25 kDa (SNAP-25), synaptobrevin, and syntaxin, form the core of a ubiquitous membrane fusion machine that interacts with the soluble proteins N-ethylmaleimide-sensitive factor (NSF) and a-SNAP. Rab proteins, in coordination with the core fusion machinery and Munc-18, help to mediate vesicle docking and fusion. There exist over 40 Rab proteins that have been described in mammals. Rab 11 is a known marker for protein trafficking, sorting, and recycling in the endosomal pathway.
TRUSTED_SUSTAINABILITY

Specifications

Antigen RAB11B
Applications Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1.67 mg/mL
Conjugate Unconjugated
Formulation PBS with 20% glycerol and 0.025% ProClin 300; pH 7
Gene Rab11b
Gene Accession No. O35509, P46638, Q15907
Gene Alias A730055L17Rik; GTP-binding protein YPT3; H-YPT3; RAB11B; RAB11B, member of RAS oncogene family; RAB11B, member RAS oncogene family; RAS oncogene family protein; ras-related protein Rab-11B; YPT3
Gene Symbols Rab11b
Host Species Rabbit
Immunogen Recombinant protein encompassing a sequence within the center region of human RAB11B. The exact sequence is proprietary.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 19326, 79434, 9230
Target Species Human, Mouse, Rat
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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