Invitrogen™ RAB11FIP1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA554950

Catalog No. PIPA554950

Description

Immunogen sequence: ASVPSIDSMM RKLEEMGLNL RKDQKKTKKR VSFSEQLFTE EAVAGAALLV EGHSSCPQEL NPAWSVAG Highest antigen sequence identity to the following orthologs: Mouse - 43%, Rat - 44%.

Rab11-FIP1 (Rab 11 family-interacting protein 1), also known as Rab-coupling protein (RCP), is a 1283 amino acid Rab 11 effector protein. Rab11-FIP1, by interacting with Rab GTPases, is involved in the endosomal recycling process and may play a role in controlling membrane trafficking along the phagocytic pathway and during phagocytosis. Localized to the recycling endosome, the cytoplasmic membrane and phagosome membranes, Rab11-FIP1 is expressed as five isoforms produced by alternative splicing. As the most highly expressed isoform, isoform two of Rab11-FIP1 is expressed in brain, lung, testis, small intestine, spleen and heart. Isoform two of Rab11-FIP1 also has been found to form a homooligomer and is believed to interact with many Rab GTPases, including Rab 4A, Rab 11A, Rab 11B and Rab 25.

Specifications

• Antigen: RAB11FIP1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: RAB11FIP1
• Gene Alias: 2010200K21Rik; 4833414G05Rik; CBBM; CBP; hCG_41347; NOEL1A; Rab coupling protein; Rab effector protein; RAB11 coupling protein; RAB11 family interacting protein 1; RAB11 family interacting protein 1 (class I); rab11 family-interacting protein 1; RAB11FIP1; Rab11-FIP1; rab11fip1 {ECO:0000250; rab-coupling protein; Rab-interacting recycling protein; Rcp; RGD1562965; UniProtKB:Q6WKZ4}
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 80223
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Immunocytochemistry
• Concentration: 0.1 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q6WKZ4
• Gene Symbols: RAB11FIP1
• Immunogen: Recombinant protein corresponding to Human RAB11FIP1. Recombinant protein control fragment (Product #RP-93849).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG