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RAB21 Polyclonal Antibody, Bethyl Laboratories

Catalog No. 501570728
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Catalog No. Quantity
50-157-0728 20 μL
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Catalog No. 50-157-0728 Supplier Bethyl Laboratories, Inc Supplier No. A305548AT
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Description

Rabbit Polyclonal Antibody

The recommended shelf life for this product is 1 year from date of receipt.

RAB21 is a member of a subfamily of small GTP-binding protein genes of the Ras superfamily that plays an important role in intracellular vesicular targeting. In non-polarized Caco-2 cells, RAB21 showed a general endoplasmic reticulum (ER)-like localization, while in polarized cells, RAB21 localized to apical vesicles. RAB21 has been shown to associate with integrin subunits and to be important for receptor entry into cells via RAB5/RAB21 endosomes. The GTPase-activating protein p120RasGAP regulates cell motility by controlling the return of the endocytosed integrins to the plasma membrane by competing with RAB21 for binding to overlapping sites on the Alpha-tail of endocytosed integrin.

Specifications

Antigen RAB21
Applications Western Blot
Classification Polyclonal
Conjugate Unconjugated
Formulation TBS with 0.1% BSA and 0.09% sodium azide
Gene RAB21
Gene Accession No. P35282, Q9UL25
Gene Alias RAB21, Ras-related protein Rab-21
Gene Symbols Rab21
Host Species Rabbit
Immunogen Between 172 and 222
Purification Method Antigen affinity chromatography
Quantity 20 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 216344, 23011
Target Species Human, Mouse
Content And Storage 4° C
Product Type Antibody
Form Liquid
Isotype IgG
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