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Invitrogen™ RAB3GAP1 Polyclonal Antibody
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Catalog No. PIPA537026
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100 μL
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Catalog No. Quantity
PIPA537026 100 μL
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Catalog No. PIPA537026 Supplier Invitrogen™ Supplier No. PA537026
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Description

Rabbit Polyclonal Antibody

This antibody detects endogenous protein at a molecular weight of 111 kDa. Purity is >95% by SDS-PAGE.

RAB3GAP1, is a 981 amino acid protein that belongs to the Rab3-GAP catalytic subunit family. Rab 3 GAP p130 converts active RAB3-GTP to the inactive form RAB3-GDP, and is required for normal eye and brain development. Defects in Rab 3 GAP p130 are the cause of Warburg micro syndrome 1 (WARBM1). WARBM1 is a severe autosomal recessive disorder characterized by developmental abnormalities of the eye and central nervous system and by microgenitalia. The Rab 3 GAP p130 protein may participate in neurodevelopmental processes such as proliferation, migration and differentiation before synapse formation, and non-synaptic vesicular release of neurotransmitters.
TRUSTED_SUSTAINABILITY

Specifications

Antigen RAB3GAP1
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.2
Gene RAB3GAP1
Gene Accession No. P69735, Q15042, Q80UJ7
Gene Alias 1700003B17Rik; 4732493F09Rik; AL117896; KIAA0066; P130; Rab 3 GAP p130; Rab3 GAP p130; RAB3 GTPase activating protein catalytic subunit 1; RAB3 GTPase activating protein subunit 1; RAB3 GTPase activating protein subunit 1 (catalytic); RAB3 GTPase-activating protein 130 kDa subunit; Rab3 GTPase-activating protein catalytic subunit; RAB3GAP; Rab3-GAP; Rab3-GAP p130; Rab3gap1; RAB3GAP130; RGD1306487; WARBM1
Gene Symbols RAB3GAP1
Host Species Rabbit
Immunogen Synthetic peptide corresponding to amino acids 580-625 of human RAB3GAP1.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 226407, 22930, 304759
Target Species Human, Mouse, Rat
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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