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Invitrogen™ RAB5 Polyclonal Antibody
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Catalog No. 01674578
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Catalog No. Quantity
01-674-578 100 μL
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Catalog No. 01-674-578 Supplier Invitrogen™ Supplier No. PA3915
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Description

Rabbit Polyclonal Antibody

PA3-915 detects Rab5 from human and rat samples. PA3-915 has been successfully used in Western blot and immunofluorescence procedures. The PA3-915 immunogen is recombinant human Rab5.

RAB5 are among the small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different sets of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. RAB5A is required for the fusion of plasma membranes and early endosomes. Contributes to the regulation of filopodia extension. Required for the exosomal release of SDCBP, CD63, PDCD6IP and syndecan. Regulates maturation of apoptotic cell-containing phagosomes, probably downstream of DYN2 and PIK3C3.
TRUSTED_SUSTAINABILITY

Specifications

Antigen RAB5
Applications Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration Conc. Not Determined
Conjugate Unconjugated
Formulation Whole Serum with 0.05% sodium azide
Gene RAB5A
Gene Accession No. M0RC99, P20339
Gene Alias 2410015H04Rik; AI663973; AU021172; nnyRab5a; Rab 5; Rab 5A; RAB5; RAB5A; RAB5A, member RAS oncogene family; Ras related protein; RAS-associated protein RAB5A; ras-related protein Rab-5A; Small GTP-binding protein rab5
Gene Symbols RAB5A
Host Species Rabbit
Immunogen Recombinant human Rab5.
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 5868, 64633
Target Species Human, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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