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MilliporeSigma™ Rabbit anti-Aspa/Nur7, Polyclonal,

Catalog No. ABN1698MI Shop All MilliporeSigma Products
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ABN1698MI 100 μg
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Catalog No. ABN1698MI Supplier MilliporeSigma™ Supplier No. ABN1698
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Description

Rabbit Polyclonal Antibody

Specifically detects Aspa/Nur7 in Human, Mouse, Rat samples, and it is validated for Immunohistochemistry, Western Blotting

Aspartoacylase (EC 3.5.1.15; UniProt Q8R3P0; also known as Acy-2, Aminoacylase-2, Nur-7) is encoded by the Aspa (also known as Acy2) gene (Gene ID 11484) in murine species. Aspartoacylase catalyzes the deacetylation of N-acetylaspartate (NAA) to generate free acetate in the central nervous system (CNS). Mutations in the ASPA gene cause the autosomal recessive neurodegenerative Canavan disease (CD) that results in inadequate lipid/myelin synthesis during development. Immunohistochemical staining reveals that aspartoacylase colocalizes with the oligodendrocyte marker CC1 throughout the brain, indicating its role in myelination.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Aspa/Nur7
Applications Immunohistochemistry, Western Blot
Classification Polyclonal
Formulation Purified rabbit polyclonal antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Accession No. Q8R3P0
Gene Symbols Aspa
Host Species Rabbit
Immunogen N-terminally his-tagged full-length recombinant mouse Aspa/Nur7.
Purification Method Protein G Purified
Quantity 100 μg
Regulatory Status RUO
Research Discipline Neuroscience
Primary or Secondary Primary
Gene ID (Entrez) NP_075602
Target Species Human, Mouse, Rat
Content And Storage Stable for one year at 2°C to 8°C from date of receipt.
Form Purified
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For Research Use Only

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