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BAI1 Rabbit anti-Human, Monkey, Polyclonal Antibody, Abnova™

Catalog No. 89127208 Shop All Abnova Corporation Products
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89-127-208 50 μg
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Catalog No. 89-127-208 Supplier Abnova Corporation Supplier No. PAB25592
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Description

Rabbit polyclonal antibody raised against synthetic peptide of BAI1.

Angiogenesis is controlled by a local balance between stimulators and inhibitors of new vessel growth and is suppressed under normal physiologic conditions. Angiogenesis has been shown to be essential for growth and metastasis of solid tumors. In order to obtain blood supply for their growth, tumor cells are potently angiogenic and attract new vessels as results of increased secretion of inducers and decreased production of endogenous negative regulators. BAI1 contains at least one 'functional' p53-binding site within an intron, and its expression has been shown to be induced by wildtype p53. There are two other brain-specific angiogenesis inhibitor genes, designated BAI2 and BAI3 which along with BAI1 have similar tissue specificities and structures, however only BAI1 is transcriptionally regulated by p53. BAI1 is postulated to be a member of the secretin receptor family, an inhibitor of angiogenesis and a growth suppressor of glioblastomas [provided by RefSeq]

Specifications

Antigen BAI1
Applications Immunohistochemistry (PFA fixed)
Classification Polyclonal
Conjugate Unconjugated
Description Rabbit polyclonal antibody raised against synthetic peptide of BAI1.
Dilution Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (15 ug/mL) The optimal working dilution should be determined by the end user.
Formulation In PBS (0.09% sodium azide)
Gene BAI1
Gene Alias FLJ41988
Gene Symbols BAI1
Host Species Rabbit
Immunogen A synthetic peptide corresponding to 16 amino acids at C-terminus of human BAI1.
Purification Method Immunoaffinity chromatography
Quantity 50 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 575
Test Specificity BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Target Species Human, Monkey
Content And Storage Store at 4°C. For long term storage store at -80°C.
Aliquot to avoid repeated freezing and thawing.
Form Liquid
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For Research Use Only

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