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BCAR3, Rabbit, Polyclonal Antibody, Abnova™

Catalog No. 89127258 Shop All Abnova Corporation Products
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100 μg
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89-127-258 100 μg
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Catalog No. 89-127-258 Supplier Abnova Corporation Supplier No. PAB25641
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Description

Rabbit polyclonal antibody raised against synthetic peptide of BCAR3.

Breast tumors are initially dependent on estrogens for growth and progression and can be inhibited by anti-estrogens such as tamoxifen. However, breast cancers progress to become anti-estrogen resistant. Breast cancer anti-estrogen resistance gene 3 was identified in the search for genes involved in the development of estrogen resistance. The gene encodes a component of intracellular signal transduction that causes estrogen-independent proliferation in human breast cancer cells. The protein contains a putative src homology 2 (SH2) domain, a hall mark of cellular tyrosine kinase signaling molecules, and is partly homologous to the cell division cycle protein CDC48. [provided by RefSeq

Specifications

Antigen BCAR3
Applications ELISA, Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Description Rabbit polyclonal antibody raised against synthetic peptide of BCAR3.
Dilution Western Blot (1-2 ug/mL) The optimal working dilution should be determined by the end user.
Formulation In PBS (0.05% sodium azide)
Gene BCAR3
Gene Accession No. NP_003558
Gene Alias KIAA0554/NSP2/SH2D3B
Gene Symbols BCAR3
Host Species Rabbit
Immunogen A synthetic peptide corresponding to 16 amino acids at N-terminus of human BCAR3.
Purification Method Peptide affinity purification
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 8412
Test Specificity At least four isoforms of BCAR3 are known to exist; this antibody will only recognize the largest isoform. BCAR3 antibody is predicted to not cross-react with other BCAR proteins.
Target Species Human, Mouse, Rat
Content And Storage Store at 4°C for three months. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
Form Liquid
Isotype IgG
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For Research Use Only

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