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MilliporeSigma™ Rabbit anti-beta-Actin, Clone: RM112,

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MABT523MI 100 μL
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Description

Rabbit Monoclonal Antibody

Specifically detects beta-Actin clone: RM112 in Human samples, and it is validated for Immunocytochemistry, Western Blotting

Actin is a 43kDa highly conserved structural protein. There are three main actin isotypes (alpha, beta and gamma) which show 90% amino-acid (aa) homology between isotypes and 98% homology within members of a particular isotypic group. The majority of the isotype heterogeneity is located in the amino-terminal 30 aa. The different actin isotypes have been shown to behave very differently in vitro and in vivo. Recent studies describe differential subcellular localization of gamma-actin and isotype specific binding of actin associated proteins. Beta actin is one of the two nonmuscle cytoskeletal actins and is relatively stable and appears to remain at normal levels regardless of experimental treatment. It is generally used as an internal control for experiments.
TRUSTED_SUSTAINABILITY

Specifications

Antigen beta-Actin
Applications Immunocytochemistry, Western Blot
Classification Monoclonal
Clone RM112
Formulation Rabbit monoclonal in PBS with 1% BSA and 0.09% sodium azide.
Gene Accession No. P60709
Gene Symbols ACTB
Host Species Rabbit
Immunogen A peptide corresponding to the N-terminus of beta-Actin.
Purification Method Protein A Purfied
Quantity 100 μL
Regulatory Status RUO
Research Discipline Cell Structure
Primary or Secondary Primary
Target Species Human
Content And Storage Stable for one year at 2°C to 8°C from date of receipt.
Form Purified
Isotype IgG
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For Research Use Only

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