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DDR1 Rabbit anti-Human, Monkey, Polyclonal Antibody, Abnova™

Rabbit polyclonal antibody raised against synthetic peptide of DDR1.

Manufacturer:  Abnova Corporation PAB16328

Catalog No. 89-118-200


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Description

Description

Receptor tyrosine kinases (RTKs) play a key role in the communication of cells with their microenvironment. These molecules are involved in the regulation of cell growth, differentiation and metabolism. The protein encoded by this gene is a RTK that is widely expressed in normal and transformed epithelial cells and is activated by various types of collagen. This protein belongs to a subfamily of tyrosine kinase receptors with a homology region to the Dictyostelium discoideum protein discoidin I in their extracellular domain. Its autophosphorylation is achieved by all collagens so far tested (type I to type VI). In situ studies and Northern-blot analysis showed that expression of this encoded protein is restricted to epithelial cells, particularly in the kidney, lung, gastrointestinal tract, and brain. In addition, this protein is significantly over-expressed in several human tumors from breast, ovarian, esophageal, and pediatric brain. This gene is located on chromosome 6p21.3 in proximity to several HLA class I genes. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq

Specifications

Specifications

DDR1
Unconjugated
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (15-20 ug/mL) The optimal working dilution should be determined by the end user.
DDR1
Liquid
DDR1
A synthetic peptide (conjugated with KLH) corresponding to human DDR1.
50 ug
Store at 4°C. For long term storage store at -80°C.
Aliquot to avoid repeated freezing and thawing.
Polyclonal
N-terminal region of human.
Immunohistochemistry (PFA fixed)
Rabbit polyclonal antibody raised against synthetic peptide of DDR1.
In PBS (0.09% sodium azide)
Q08345
CAK|CD167|DDR|EDDR1|MCK10|NEP|NTRK4|PTK3|PTK3A|RTK6|TRKE
Rabbit
Immunoaffinity purification
RUO
Primary
780
Human, Monkey
SDS
Documents
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