EP300 (phospho S89), Rabbit anti-Human, Polyclonal Antibody, Abnova™

Catalog No.	Quantity
89-114-237	400 μL

Catalog No. 89-114-237 Supplier Abnova Corporation Supplier No. PAB0461

Description

Rabbit polyclonal antibody raised against synthetic phosphopeptide of EP300.

This gene encodes the adenovirus E1A-associated cellular p300 transcriptional co-activator protein. It functions as histone acetyltransferase that regulates transcription via chromatin remodeling and is important in the processes of cell proliferation and differentiation. It mediates cAMP-gene regulation by binding specifically to phosphorylated CREB protein. This gene has also been identified as a co-activator of HIF1A (hypoxia-inducible factor 1 alpha), and thus plays a role in the stimulation of hypoxia-induced genes such as VEGF. Defects in this gene are a cause of Rubinstein-Taybi syndrome and may also play a role in epithelial cancer. [provided by RefSeq

Specifications

• Antigen: EP300
• Applications: Dot Blot, ELISA, Immunohistochemistry (Paraffin), Western Blot
• Classification: Polyclonal
• Conjugate: Unconjugated
• Description: Rabbit polyclonal antibody raised against synthetic phosphopeptide of EP300.
• Dilution: Dot Blot (1:500) Immunohistochemistry (1:50-100) The optimal working dilution should be determined by the end user.
• Formulation: In PBS (0.09% sodium azide)
• Gene: EP300
• Gene Accession No.: NP_001420;Q09472
• Gene Alias: KAT3B/p300
• Gene Symbols: EP300
• Host Species: Rabbit
• Immunogen: Synthetic phosphopeptide (conjugated with KLH) corresponding to residues surrounding S89 of human EP300.
• Purification Method: Protein G purification
• Quantity: 400 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 2033
• Target Species: Human
• Content And Storage: Store at 4°C. For long term storage store at -20°C.
  Aliquot to avoid repeated freezing and thawing.
• Form: Liquid

For Research Use Only