FGFR2 Rabbit anti-Human, Mouse, Polyclonal Antibody, Abnova™

Catalog No.	Quantity
89-128-716	100 μL

Catalog No. 89-128-716 Supplier Abnova Corporation Supplier No. PAB27066

Description

Rabbit polyclonal antibody raised against synthetic peptide of FGFR2.

The protein encoded by this gene is a member of the fibroblast growth factor receptor family, where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein consists of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. This particular family member is a high-affinity receptor for acidic, basic and/or keratinocyte growth factor, depending on the isoform. Mutations in this gene are associated with Crouzon syndrome, Pfeiffer syndrome, Craniosynostosis, Apert syndrome, Jackson-Weiss syndrome, Beare-Stevenson cutis gyrata syndrome, Saethre-Chotzen syndrome, and syndromic craniosynostosis. Multiple alternatively spliced transcript variants encoding different isoforms have been noted for this gene. [provided by RefSeq

Specifications

• Antigen: FGFR2
• Applications: Immunohistochemistry (PFA fixed), Western Blot
• Classification: Polyclonal
• Conjugate: Unconjugated
• Description: Rabbit polyclonal antibody raised against synthetic peptide of FGFR2.
• Dilution: Western Blot (1:500-1:1000) Immunohistochemistry (1:50-1:200) The optimal working dilution should be determined by the end user.
• Formulation: In PBS, pH 7.2 (0.09% sodium azide)
• Gene: FGFR2
• Gene Accession No.: P21802
• Gene Alias: BEK/BFR-1/CD332/CEK3/CFD1/ECT1/FLJ98662/JWS/K-SAM/KGFR/TK14/TK25
• Gene Symbols: FGFR2
• Host Species: Rabbit
• Immunogen: A synthetic peptide corresponding to human FGFR2.
• Purification Method: Antigen affinity purification
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 2263
• Test Specificity: FGFR2 polyclonal antibody detects endogenous levels of FGFR2 protein.
• Target Species: Human, Mouse
• Content And Storage: Store at 4°C. For long term storage store at -20°C.
  Aliquot to avoid repeated freezing and thawing.
• Form: Liquid

For Research Use Only