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MEF2A (phospho S408), Rabbit anti-Human, Mouse, Rat, Polyclonal Antibody, Abnova™

Rabbit polyclonal antibody raised against synthetic phosphopeptide of MEF2A.

Manufacturer:  Abnova Corporation PAB25881

Catalog No. 89-127-512


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Description

Description

The process of differentiation from mesodermal precursor cells to myoblasts has led to the discovery of a variety of tissue-specific factors that regulate muscle gene expression. The myogenic basic helix-loop-helix proteins, including myoD (MIM 159970), myogenin (MIM 159980), MYF5 (MIM 159990), and MRF4 (MIM 159991) are one class of identified factors. A second family of DNA binding regulatory proteins is the myocyte-specific enhancer factor-2 (MEF2) family. Each of these proteins binds to the MEF2 target DNA sequence present in the regulatory regions of many, if not all, muscle-specific genes. The MEF2 genes are members of the MADS gene family (named for the yeast mating type-specific transcription factor MCM1, the plant homeotic genes 'agamous' and 'deficiens' and the human serum response factor SRF (MIM 600589)), a family that also includes several homeotic genes and other transcription factors, all of which share a conserved DNA-binding domain.[supplied by OMIM

Sequence: P-I-Sp-P-P
Specifications

Specifications

MEF2A
1 mg/mL
Rabbit polyclonal antibody raised against synthetic phosphopeptide of MEF2A.
In PBS (without Mg2+ and Ca2+), 150mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide)
Liquid
MEF2A
Synthetic phosphopeptide corresponding to residues surrounding S408 of human MEF2A.
100 ug
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.
Polyclonal
Human, Murine, Rat
Immunohistochemistry (PFA fixed)
Unconjugated
Immunohistochemistry (1:50-1:100) The optimal working dilution should be determined by the end user.
MEF2A
ADCAD1|RSRFC4|RSRFC9
Rabbit
Affinity chromatography
RUO
Primary
4205
SDS
Documents
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