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NFKB1 (phospho S893), Rabbit anti-Human, Polyclonal Antibody, Abnova™

Catalog No. 89126907 Shop All Abnova Corporation Products
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89-126-907 100 μg
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Catalog No. 89-126-907 Supplier Abnova Corporation Supplier No. PAB25239
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Description

Rabbit polyclonal antibody raised against synthetic phosphopeptide of NFKB1.

This gene encodes a 105kDa protein which can undergo cotranslational processing by the 26S proteasome to produce a 50kDa protein. The 105kDa protein is a Rel protein-specific transcription inhibitor and the 50kDa protein is a DNA binding subunit of the NF-kappa-B (NFKB) protein complex. NFKB is a transcription regulator that is activated by various intra- and extra-cellular stimuli such as cytokines, oxidant-free radicals, ultraviolet irradiation, and bacterial or viral products. Activated NFKB translocates into the nucleus and stimulates the expression of genes involved in a wide variety of biological functions. Inappropriate activation of NFKB has been associated with a number of inflammatory diseases while persistent inhibition of NFKB leads to inappropriate immune cell development or delayed cell growth. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq

Sequence: A-S-Sp-P-V

Specifications

Antigen NFKB1
Applications Immunofluorescence, Immunohistochemistry (PFA fixed)
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Description Rabbit polyclonal antibody raised against synthetic phosphopeptide of NFKB1.
Dilution Immunohistochemistry (1:50-1:100) Immunofluorescence (1:100-1:200) The optimal working dilution should be determined by the end user.
Formulation In PBS (without Mg2+ and Ca2+), 150mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide)
Gene NFKB1
Gene Alias DKFZp686C01211/EBP-1/KBF1/MGC54151/NF-kappa-B/NFKB-p105/NFKB-p50/p105/p50
Gene Symbols NFKB1
Host Species Rabbit
Immunogen Synthetic phosphopeptide corresponding to residues surrounding S893 of human NFKB1.
Purification Method Affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 4790
Target Species Human
Content And Storage Store at -20°C.
Aliquot to avoid repeated freezing and thawing.
Form Liquid
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For Research Use Only

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