NFKBIB Rabbit anti-Human, Polyclonal Antibody, Abnova™

Catalog No.	Quantity
89-120-319	100 μg

Catalog No. 89-120-319 Supplier Abnova Corporation Supplier No. PAB18763

Description

Rabbit polyclonal antibody raised against synthetic peptide of NFKBIB.

NFKB1 (MIM 164011) or NFKB2 (MIM 164012) is bound to REL (MIM 164910), RELA (MIM 164014), or RELB (MIM 604758) to form the NFKB complex. The NFKB complex is inhibited by I-kappa-B proteins (NFKBIA, MIM 164008, or NFKBIB), which inactivate NF-kappa-B by trapping it in the cytoplasm. Phosphorylation of serine residues on the I-kappa-B proteins by kinases (IKBKA, MIM 600664 or IKBKB, MIM 603258) marks them for destruction via the ubiquitination pathway, thereby allowing activation of the NF-kappa-B complex. Activated NFKB complex translocates into the nucleus and binds DNA at kappa-B-binding motifs such as 5-prime GGGRNNYYCC 3-prime or 5-prime HGGARNYYCC 3-prime (where H is A, C, or T; R is an A or G purine; and Y is a C or T pyrimidine).[supplied by OMIM

Specifications

• Antigen: NFKBIB
• Applications: ELISA, Western Blot
• Classification: Polyclonal
• Conjugate: Unconjugated
• Description: Rabbit polyclonal antibody raised against synthetic peptide of NFKBIB.
• Dilution: ELISA (1:20000-1:80000) Western Blot (1:200-1:1000) The optimal working dilution should be determined by the end user.
• Formulation: In buffer containing 0.02% sodium azide
• Gene: NFKBIB
• Gene Alias: IKBB/TRIP9
• Gene Symbols: NFKBIB
• Host Species: Rabbit
• Immunogen: A synthetic peptide corresponding to 14 amino acids at C-terminus of human NFKBIB.
• Quantity: 100 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 4793
• Target Species: Human
• Content And Storage: Store at 4°C for three months. For long term storage store at -20°C.
  Aliquot to avoid repeated freezing and thawing.
• Form: Liquid

For Research Use Only