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Description
This gene product is a nuclear-encoded mitochondrial protein with similarity to dynamin-related GTPases. It is a component of the mitochondrial network. Mutations in this gene have been associated with optic atrophy type 1, which is a dominantly inherited optic neuropathy resulting in progressive loss of visual acuity, leading in many cases to legal blindness. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
Specifications
Specifications
| Antigen | OPA1 |
| Applications | Immunohistochemistry, Western Blot |
| Classification | Polyclonal |
| Conjugate | Unconjugated |
| Description | Rabbit polyclonal antibody raised against synthetic peptide of OPA1. |
| Dilution | Western Blot (2 ug/mL) Immunohistochemistry (2.5 ug/mL) The optimal working dilution should be determined by the end user. |
| Formulation | In Tris-glycine, 150mM NaCl (0.05% sodium azide) |
| Gene | OPA1 |
| Gene Alias | FLJ12460/KIAA0567/MGM1/NPG/NTG/largeG |
| Gene Symbols | OPA1 |
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