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PDGFRB (phospho Y751), Rabbit anti-Human, Mouse, Rat, Polyclonal Antibody, Abnova™

Catalog No. 89118756 Shop All Abnova Corporation Products
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89-118-756 100 μg
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Catalog No. 89-118-756 Supplier Abnova Corporation Supplier No. PAB16955
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Description

Rabbit polyclonal antibody raised against synthetic phosphopeptide of PDGFRB.

This gene encodes a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. This gene is flanked on chromosome 5 by the genes for granulocyte-macrophage colony-stimulating factor and macrophage-colony stimulating factor receptor; all three genes may be implicated in the 5-q syndrome. A translocation between chromosomes 5 and 12, that fuses this gene to that of the translocation, ETV6, leukemia gene, results in chronic myeloproliferative disorder with eosinophilia. [provided by RefSeq

Specifications

Antigen PDGFRB
Applications ELISA, Immunohistochemistry (PFA fixed), Western Blot
Classification Polyclonal
Conjugate Unconjugated
Description Rabbit polyclonal antibody raised against synthetic phosphopeptide of PDGFRB.
Dilution Western Blot (1:500-1:1000) Immunohistochemistry (1:50-1:100) ELISA (1:4000) The optimal working dilution should be determined by the end user.
Formulation In 20mM PBS, 0.15M NaCl, pH 7.2 (0.01% sodium azide)
Gene PDGFRB
Gene Alias CD140B/JTK12/PDGF-R-beta/PDGFR/PDGFR1
Gene Symbols PDGFRB
Host Species Rabbit
Immunogen Synthetic phosphopeptide corresponding to residues surrounding Y751 of human PDGFRB.
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 5159
Test Specificity This antibody detects endogenous levels of PDGFRB only when phosphorylated at tyrosine 751.
Target Species Human, Mouse, Rat
Content And Storage Store at 4°C for three months. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
Form Liquid
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For Research Use Only

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