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RB1 (phospho S612), Rabbit anti-Human, Polyclonal Antibody, Abnova™

Catalog No. 89114294 Shop All Abnova Corporation Products
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400 μL
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89-114-294 400 μL
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Catalog No. 89-114-294 Supplier Abnova Corporation Supplier No. PAB0597
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Description

Rabbit polyclonal antibody raised against synthetic phosphopeptide of RB1.

The protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma. [provided by RefSeq

Specifications

Antigen RB1
Applications ELISA, Immunohistochemistry, Western Blot
Classification Polyclonal
Conjugate Unconjugated
Description Rabbit polyclonal antibody raised against synthetic phosphopeptide of RB1.
Dilution Western Blot (1:1000) Immunohistochemistry (1:50-100) The optimal working dilution should be determined by the end user.
Formulation In PBS (0.09% sodium azide)
Gene RB1
Gene Alias OSRC/RB/p105-Rb/pRb/pp110
Gene Symbols RB1
Host Species Rabbit
Immunogen Synthetic phosphopeptide (conjugated with KLH) corresponding to residues surrounding S612 of human RB1.
Purification Method Protein G purification
Quantity 400 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 5925
Target Species Human
Content And Storage Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
Form Liquid
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For Research Use Only

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