STAT2 (phospho Y690), Rabbit anti-Human, Mouse, Rat, Polyclonal Antibody, Abnova™

Rabbit polyclonal antibody raised against synthetic phosphopeptide of STAT2.

Supplier:  Abnova Corporation PAB11305

Catalog No. 89-115-006

Description

The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. In response to interferon (IFN), this protein forms a complex with STAT1 and IFN regulatory factor family protein p48 (ISGF3G), in which this protein acts as a transactivator, but lacks the ability to bind DNA directly. Transcription adaptor P300/CBP (EP300/CREBBP) has been shown to interact specifically with this protein, which is thought to be involved in the process of blocking IFN-alpha response by adenovirus. [provided by RefSeq

Specifications

• Antigen: STAT2
• Classification: Polyclonal
• Description: Rabbit polyclonal antibody raised against synthetic phosphopeptide of STAT2.
• Formulation: In 20mM KH₂PO₄, 150mM NaCl, pH 7.2 (0.01% sodium azide)
• Gene Alias: ISGF-3/MGC59816/P113/STAT113
• Host Species: Rabbit
• Quantity: 100 μg
• Primary or Secondary: Primary
• Test Specificity: This affinity purified antibody is directed against human STAT2 pY690 protein.
• Content And Storage: Store at 4°C. For long term storage store at -20°C.
  Aliquot to avoid repeated freezing and thawing.

• Applications: ELISA, Western Blot
• Conjugate: Unconjugated
• Dilution: ELISA (1:85000) Western Blot (1:500-1:1000) The optimal working dilution should be determined by the end user.
• Gene: STAT2
• Gene Symbols: STAT2
• Immunogen: Synthetic phosphopeptide corresponding to residues surrounding Y690 of human STAT2.
• Regulatory Status: RUO
• Gene ID (Entrez): 6773
• Target Species: Human, Mouse, Rat
• Form: Liquid

For Research Use Only