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RAD21 Monoclonal Antibody (OTI11F10), TrueMAB™, OriGene
SDP

Catalog No. 501683885
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100 μL
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Catalog No. Quantity
50-168-3885 100 μL
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Catalog No. 50-168-3885 Supplier OriGene Supplier No. TA811186
May include imposed supplier surcharges.
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Description

Mouse Monoclonal Antibody

The cohesin complex plays an important role in tethering sister chromatids during the prophase through anaphase stages of mitosis, making certain that genomic information is replicated accurately. As the cellular division process continues, separase destroys the cohesin complex by means of cleavaging its Scc1 subunit, allowing the chromatids to separate and divide with the cell. During apoptosis the C-terminal portion of hRad21 is cleaved and translocated to the cytoplasm. This cleavage and translocation may act as a nuclear signal that promotes and accelerates subsequent events of apoptosis.

Specifications

Antigen RAD21
Applications Western Blot
Classification Monoclonal
Clone OTI11F10
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene RAD21
Gene Accession No. O60216
Gene Alias CDLS4, HR21, HRAD21, MCD1, NXP1, SCC1, hHR21
Gene Symbols RAD21
Host Species Mouse
Immunogen Human recombit protein fragment corresponding to amino acids 193-458 of human RAD21 produced in E.coli.
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 5885
Target Species Human
Content And Storage -20° C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG1
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