RAD23B Monoclonal Antibody (OTI13A3), TrueMAB™, OriGene

Mouse Monoclonal Antibody

Supplier:  OriGene TA804864

Catalog No. 50-168-0448

Description

The protein encoded by this gene is one of two human homologs of Saccharomyces cerevisiae Rad23, a protein involved in the nucleotide excision repair (NER). This protein was found to be a component of the protein complex that specifically complements the NER defect of xeroderma pigmentosum group C (XP-c) cell extracts in vitro. This protein was also shown to interact with, and elevate the nucleotide excision activity of 3-methyladenine-DNA glycosylase (MPG), which suggested a role in DNA damage recognition in base excision repair. This protein contains an N-terminal ubiquitin-like domain, which was reported to interact with 26S proteasome, and thus this protein may be involved in the ubiquitin mediated proteolytic pathway in cells.

Specifications

• Antigen: RAD23B
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
• Gene Accession No.: P54727
• Gene Symbols: RAD23B
• Immunogen: Human recombit protein fragment corresponding to amino acids 1-253 of human RAD23B produced in E.coli.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1

• Applications: Western Blot
• Clone: OTI13A3
• Conjugate: Unconjugated
• Gene: RAD23B
• Gene Alias: HHR23B, HR23B, P58
• Host Species: Mouse
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 5887
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Form: Liquid