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Invitrogen™ RAD51 Monoclonal Antibody (14B4)
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Catalog No. MA123271
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100 μL
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MA123271 100 μL
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Catalog No. MA123271 Supplier Invitrogen™ Supplier No. MA123271
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Description

Mouse Monoclonal Antibody

A suggested positive control for this product is T24.

RAD51 plays a critical role in homologous strand exchange, a key step in DNA repair through homologous recobination. It binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. RAD51 catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. It binds to a single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange. Mutations in the gene can results in breast cancer, mirror movements 2 and fanconi anemia.
TRUSTED_SUSTAINABILITY

Specifications

Antigen RAD51
Applications Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot, Proximity Ligation Assay, Immunocytochemistry
Classification Monoclonal
Clone 14B4
Concentration 1.0 mg/mL
Conjugate Unconjugated
Formulation PBS with no preservative; pH 7
Gene Rad51
Gene Accession No. P37383, Q06609, Q08297
Gene Alias AV304093; BRCA1/BRCA2-containing complex, subunit 5; BRCC5; DNA repair protein RAD51; DNA repair protein RAD51 homolog 1; DNA repair protein RAD51 homolog A; DNA repair protein rhp51; FANCR; homolog to S.cerevisiae; HRAD51; HsRad51; HsT16930; MGC128559 protein; MRMV2; MUT5; rad51; RAD51 homolog; RAD51 homolog (RecA homolog); RAD51 homolog (RecA homolog, E. coli); RAD51 homolog A; RAD51 recombinase; RAD51 recombinase L homeolog; rad51.1; rad51.L; rad51-1; RAD51A; rad51-a; rad51-b; Reca; RecA family recombinase Rhp51; RecA, E. coli, homolog of; RecA-like protein; recombinase RAD51; recombination protein A; RGD1563603; rhp51; SPAC644.14c; wu:fb38e12; xrad51; XRad51.1; YER095W; zgc:77754
Gene Symbols Rad51
Host Species Mouse
Immunogen Full length (amino acids 1-338) Rad51 expressed in E. coli.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 19361, 396086, 499870, 5888
Target Species Human, Mouse, Rat, Chicken
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG2a
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