Invitrogen™ RAD51C Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA565401

Catalog No. PIPA565401

Description

Immunogen sequence: MRGKTFRFEMQ RDLVSFPLSP AVRVKLVSAG FQTAEELLEV KPSELSKEVG ISKAEALETL QIIRRECLTN KPRYAGTSES HKKCTALELL EQEHTQGFII TFCSALDDIL GGGVPLMKTT EICGAPGVG Highest antigen sequence identity to the following orthologs - mouse 79%, rat 82%.

ZFPM1 is a transcription regulator that plays an essential role in erythroid and megakaryocytic cell differentiation. ZFPM1 is an essential cofactor that acts via the formation of a heterodimer with transcription factors of the GATA family GATA1, GATA2 and GATA3. Such heterodimer can both activate or repress transcriptional activity, depending on the cell and promoter context. The heterodimer formed with GATA proteins is essential to activate expression of genes such as NFE2, ITGA2B, alpha- and beta-globin, while it represses expression of KLF1. ZFPM1 may be involved in regulation of some genes in gonads. ZFPM1 may also be involved in cardiac development, in a non-redundant way with ZFPM2/FOG2.

Specifications

• Antigen: RAD51C
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: RAD51C
• Gene Alias: BROVCA3; DNA repair protein RAD51 homolog 3; FANCO; MGC104277; R51H3; RAD51 homolog C; RAD51 paralog C; RAD51C; RAD51L2; RAD51-like protein 2; RGD1563765; yeast RAD51 homolog 3
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 5889
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunocytochemistry
• Concentration: 0.6 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: O43502
• Gene Symbols: RAD51C
• Immunogen: Recombinant Human RAD51C. Recombinant protein control fragment (Product #RP-106082).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov