Radixin Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Supplier:  Proteintech Group Inc 137901AP150UL

Catalog No. 50-172-9008

Description

Ezrin, radixin and moesin (ERM) proteins are widely distributed proteins located in the cellular cortex, in microvilli and adherens junctions. They are mediate linkage of actin cytoskeleton to plasma membrane in many cells. ERM proteins contain an N-terminal FERM (4.1/ezrin/radixin/moesin) domain that binds to phosphatidylinositol-(4, 5)phosphate and cellular membrane proteins. The ERM, particularly ezrin, is important for reconstructing cell-surface architecture during T cell activation. Despite the high degree of homology, the three proteins exhibit a distinct receptor-specific pattern of phosphorylation. ERM activity is regulated in part by phosphorylation at a C-terminal threonine (ezrin-Thr567, radixin-Thr564, moesin-Thr558).

Specifications

• Antigen: Radixin
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: RDX
• Gene Alias: DFNB24, radixin, RDX
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 19684, 315655, 5962
• Content And Storage: -20°C
• Form: Liquid

• Applications: Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
• Concentration: 0.31 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: P26043, P35241
• Gene Symbols: Rdx
• Immunogen: Radixin Fusion Protein Ag4813
• Quantity: 150 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG