RAF1 Rabbit anti-Human, Polyclonal, Proteintech

Catalog No.	Quantity
50-173-5479	150 μL

Catalog No. 50-173-5479 Supplier Proteintech Group Inc Supplier No. 268631AP150UL

Description

Rabbit Polyclonal Antibody

Transcription factor which plays a key role in defining the composition of the RNA polymerase II (RNAPII) elongation complex and in modulating the production of mature mRNA transcripts. Acts as an assembly factor to recruit various factors to the RNAPII elongation complex and is recruited to the complex via binding to the transcription elongation factor SUPT6H bound to the C-terminal domain (CTD) of the RNAPII subunit RPB1 (POLR2A). The SUPT6H:IWS1:CTD complex recruits mRNA export factors (ALYREF/THOC4, EXOSC10) as well as histone modifying enzymes (such as SETD2) to ensure proper mRNA splicing, efficient mRNA export and elongation-coupled H3K36 methylation, a signature chromatin mark of active transcription.

Specifications

• Antigen: RAF1
• Applications: Immunohistochemistry (Paraffin), Western Blot
• Classification: Polyclonal
• Concentration: 0.67 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
• Gene: RAF1
• Gene Accession No.: P04049
• Gene Alias: c Raf, CRAF, NS5, Proto oncogene c RAF, RAF, Raf 1, RAF1
• Gene Symbols: RAF1
• Host Species: Rabbit
• Immunogen: RAF1 Fusion Protein Ag25423
• Purification Method: Antigen Affinity Chromatography
• Quantity: 150 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 5894
• Target Species: Human
• Content And Storage: -20°C
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG