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Invitrogen™ RAMP1 Polyclonal Antibody
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Catalog No. PA550253
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100 μL
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PA550253 100 μL
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Catalog No. PA550253 Supplier Invitrogen™ Supplier No. PA550253
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Description

Rabbit Polyclonal Antibody

The antibody detects endogenous levels of total RAMP1 protein.

The protein encoded by this gene is a member of the RAMP family of single-transmembrane-domain proteins, called receptor (calcitonin) activity modifying proteins (RAMPs). RAMPs are type I transmembrane proteins with an extracellular N terminus and a cytoplasmic C terminus. RAMPs are required to transport calcitonin-receptor-like receptor (CRLR) to the plasma membrane. CRLR, a receptor with seven transmembrane domains, can function as either a calcitonin-gene-related peptide (CGRP) receptor or an adrenomedullin receptor, depending on which members of the RAMP family are expressed. In the presence of this (RAMP1) protein, CRLR functions as a CGRP receptor. The RAMP1 protein is involved in the terminal glycosylation, maturation, and presentation of the CGRP receptor to the cell surface.
TRUSTED_SUSTAINABILITY

Specifications

Antigen RAMP1
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 0.4 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.05% sodium azide; pH 7.4
Gene RAMP1
Gene Accession No. O60894, Q9JJ74, Q9WTJ5
Gene Alias 9130218E19Rik; calcitonin receptor-like receptor activity modifying protein 1; calcitonin-receptor-like receptor activity-modifying protein 1; CRLR activity-modifying protein 1; MGC38240; RAMP1; receptor (calcitonin) activity modifying protein 1; receptor (G protein-coupled) activity modifying protein 1; receptor activity modifying protein 1; receptor activity-modifying protein 1
Gene Symbols RAMP1
Host Species Rabbit
Immunogen Fusion protein corresponding to a region derived from internal residues of human Receptor (G protein-coupled) activity modifying protein 1.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 10267, 51801, 58965
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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