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RanBP1 Rabbit anti-Human, Polyclonal, Bethyl Laboratories

Catalog No. 501557796
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50-155-7796 100 μL
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Catalog No. 50-155-7796 Supplier Bethyl Laboratories, Inc Supplier No. A300512A
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Rabbit Polyclonal Antibody

The recommended shelf life for this product is 1 year from date of receipt.

Ran/TC4-binding protein, RanBP1, interacts specifically with GTP-charged RAN. RANBP1 encodes a 23-kD protein that binds to RAN complexed with GTP but not GDP. RANBP1 does not activate GTPase activity of RAN but does markedly increase GTP hydrolysis by the RanGTPase-activating protein (RanGAP1). The RANBP1 cDNA encodes a 201-amino acid protein that is 92% similar to its mouse homolog. In both mammalian cells and in yeast, RANBP1 acts as a negative regulator of RCC1 by inhibiting RCC1-stimulated guanine nucleotide release from RAN.

Specifications

Antigen RanBP1
Applications Immunoprecipitation, Western Blot
Classification Polyclonal
Concentration 1 mg/ml
Conjugate Unconjugated
Formulation phosphate, tris citrate with 0.09% sodium azide; pH 7-8
Gene RANBP1
Gene Accession No. P43487
Gene Alias Ran Binding Protein 1, RANG, Ran-specific GTPase-activating protein
Gene Symbols RANBP1
Host Species Rabbit
Immunogen Between 150 and C-term
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 5902
Target Species Human
Content And Storage 4° C
Product Type Antibody
Form Liquid
Isotype IgG
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