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  6. RANBP10 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech 

RANBP10 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech
SDP

Catalog No. 501733260 Shop All Proteintech Group Inc Products
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50-173-3260 150 μL
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Catalog No. 50-173-3260 Supplier Proteintech Group Inc Supplier No. 211071AP150UL
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Description

Rabbit Polyclonal Antibody

The RAN binding protein 10 (RANBP10) is a cytoplasmic guanine nucleotide exchange factor that shares high sequence similarity to the MET-interacting protein RANBP9. RANBP10 is expressed in the cytoplasm of mature megakaryocytes (MKs) and platelets where it localizes to polymerized noncentrosomal microtubules. RANBP10 possesses guanine nucleotide exchange factor activity towards RAN, a GTPase involved in nucleocytoplasmic traffic, spindle formation at mitosis, and nuclear envelope assembly during telophase, suggesting that RANBP10 may also be involved in these activities. RANBP10 depletion in vitro caused the disturbance of polymerized filaments in MKs and platelets in RANBP10-null mice exhibited disorders in microtubule filament numbers and localization, indicating that RANBP10 may play a significant role in maintaining microtubule dynamics.

Specifications

Antigen RANBP10
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 0.22 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene RANBP10
Gene Accession No. Q6VN19, Q6VN20
Gene Alias KIAA1464, RAN binding protein 10, RANBP10
Gene Symbols Ranbp10
Host Species Rabbit
Immunogen RANBP10 Fusion Protein Ag15387
Purification Method Antigen Affinity Chromatography
Quantity 150 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 361396, 57610, 74334
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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