Invitrogen™ RANBP2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA1082

Catalog No. PA1082

Description

PA1-082 detects Ran binding protein 2 (RanBP2) from human and bovine retina. PA1-082 has been successfully used in Western blot and immunohistochemistry procedures. By Western blot, this antibody detects an ~360 kDa protein representing RanBP2 from bovine retinal extracts. Immunohistochemical staining of bovine retina with PA1-082 results in cytoplasmic staining of cells within the inner nuclear layer as well as the ganglion cells. The PA1-082 immunogen is a synthetic peptide corresponding to residues M(1) R R S K A D V E R Y I A S V Q G S(18) of human RanBP2. This sequence is completely conserved between human and mouse. The PA1-082 immunizing peptide (Cat. # PEP-137) is available for use in neutralization and control experiments.

RanBP2 interacts with the small GTP-binding protein Ran and forms a large multiprotein complex involved in many biological processes such as mRNA processing, nuclear transport, cell cycle control and postmitotic nuclear reassembly. The protein is identified by western blotting as an apparent molecular mass of 360 kD. It is involved in nucleation of microtubule and control of cell growth by interacting with many protein factors.

Specifications

• Antigen: RANBP2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: RANBP2
• Gene Alias: 358 kDa nucleoporin; A430087B05Rik; acute necrotizing encephalopathy 1 (autosomal dominant); ADANE; AI256741; ANE1; E3 SUMO-protein ligase RanBP2; E3 SUMO-protein transferase RanBP2; IIAE3; Nuclear pore complex protein Nup358; nucleoporin 358; nucleoporin Nup358; NUP358; P270; RAN binding protein 2; ran-binding protein 2; RANBP2; RBP2; retina-specific cyclophilin; RGD1560047; spliced variant with Ran-binding and cyclophilin domains; transformation-related protein 2; TRP1; TRP2
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 5903, 785768
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: Immunohistochemistry, Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 1mg/mL BSA and 0.05% sodium azide
• Gene Accession No.: P48820, P49792
• Gene Symbols: RANBP2
• Immunogen: Synthetic peptide corresponding to residues M(1) R R S K A D V E R Y I A S V Q G S(18) of human RanBP2.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human, Bovine
• Product Type: Antibody
• Isotype: IgG