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Invitrogen™ RANGAP1 Monoclonal Antibody (19C7)
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Catalog No. 330800
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Catalog No. Quantity
33-080-0 100 μg
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Catalog No. 33-080-0 Supplier Invitrogen™ Supplier No. 330800
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Description

Mouse Monoclonal Antibody

RANGAP1 Monoclonal Antibody for Western Blot, ICC/IF, ELISA

Ran is a small signaling GTPase that is involved in nucleocytoplasmic transport. Two additional functions of animal Ran in the formation of spindle asters and the reassembly of the nuclear envelope in mitotic cells have been recently reported. In contrast to Ras or Rho, Ran is not associated with membranes. Instead, the spatial sequestering of its accessory proteins, the Ran GTPase-activating protein RanGAP and the nucleotide exchange factor RCC1, appears to define the local concentration of RanGTP vs. RanGDP involved in signaling. Mammalian RanGAP is bound to the nuclear pore by a mechanism involving the attachment of small ubiquitin-related modifier protein (SUMO) to its C terminus and the subsequent binding of the SUMOylated domain to the nucleoporin Nup358.
TRUSTED_SUSTAINABILITY

Specifications

Antigen RANGAP1
Applications ELISA, Western Blot, Immunocytochemistry
Classification Monoclonal
Clone 19C7
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.1% sodium azide; pH 7.4
Gene RANGAP1
Gene Accession No. P46060, P46061
Gene Alias C79654; fug1; KIAA1835; MGC20266; mKIAA1835; RAN GTPase activating protein 1; RAN GTPase activating protein 1 a; Ran GTPase activating protein 1 b; Ran GTPase activating protein 1 L homeolog; Ran GTPase activating protein 1 S homeolog; ran GTPase-activating protein 1; RANGAP; RanGAP1; rangap1.L; rangap1.S; rangap1a; rangap1-a; rangap1b; rangap1-b; rna1p; SD; segregation distorter homolog; segregation distortion; XELAEV_18023679mg; XELAEV_18025680mg
Gene Symbols RANGAP1
Host Species Mouse
Immunogen A fusion protein consisting of the first 203 amino-terminal residues of the mouse RanGAP-1 protein.
Purification Method Affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 19387, 362965, 5905
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG1 κ
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