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RanGAP1 Rabbit anti-Human, Mouse, Polyclonal, Proteintech
SDP

Catalog No. p-7212170 Shop All Proteintech Group Inc Products
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50-173-5660 150 μL
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Catalog No. 50-173-5660 Supplier Proteintech Group Inc Supplier No. 274051AP150UL
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Description

Rabbit Polyclonal Antibody

RanGAP1, is a homodimeric 65-kD polypeptide that specifically induces the GTPase activity of RAN, but not of RAS by over 1, 000-fold. RanGAP1 is the immediate antagonist of RCC1, a regulator molecule that keeps RAN in the active, GTP-bound state. The RANGAP1 gene encodes a 587-amino acid polypeptide. The sequence is unrelated to that of GTPase activators for other RAS-related proteins, but is 88% identical to Fug1, the murine homolog of yeast Rna1p. RanGAP1 and RCC1 control RAN-dependent transport between the nucleus and cytoplasm. RanGAP1 is a key regulator of the RAN GTP/GDP cycle.

Specifications

Antigen RanGAP1
Applications Western Blot
Classification Polyclonal
Concentration 0.37 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
Gene RANGAP1
Gene Accession No. P46060, P46061
Gene Alias Fug1, KIAA1835, RANGAP1, SD
Gene Symbols RANGAP1
Host Species Rabbit
Immunogen RanGAP1 Fusion Protein Ag26128
Purification Method Antigen Affinity Chromatography
Quantity 150 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 19387, 5905
Target Species Human, Mouse
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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