RARG Mouse anti-Human, Clone: OTI3G1, liquid, TrueMAB™

Mouse Monoclonal Antibody

Supplier:  OriGene TA810381

Catalog No. 50-168-3364

Description

Retinoic acid, a metabolite of vitamin A, is necessary for normal organogenesis but acts as a teratogen at high levels during embryonic and fetal development. Retinoic acid functions through its interaction with the nuclear protein, retinoic acid receptor (RAR). RAR belongs to the steroid and thyroid hormone superfamily of nuclear receptor proteins which exert their effects by binding to specific DNA response elements, thus regulating gene expression in target cells. RAR exists as three major subtypes: alpha, beta and gamma. Two main isoforms of RAR gamma exist: RAR gamma-1 has been found to be predomitly expressed in skin, while RAR gamma-2 has been found early in embryogenesis and in embryonal carcinoma cells. RAR gamma is also known as RARD. The corresponding gene for the retinoic acid receptor gamma 1 is NR1B3.

Specifications

• Antigen: RARG
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
• Gene Accession No.: P13631
• Gene Symbols: RARG
• Immunogen: Human recombit protein fragment corresponding to amino acids 1-223 of human RARG produced in E.coli.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1

• Applications: Western Blot
• Clone: OTI3G1
• Conjugate: Unconjugated
• Gene: RARG
• Gene Alias: NR1B3, RARC
• Host Species: Mouse
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 5916
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Form: Liquid