RARS Mouse anti-Human, Mouse, Rat, Clone: 1C8G4, Proteintech

Mouse Monoclonal Antibody

Catalog Number	Mfr. No.	Quantity
50-173-7206	Proteintech Group Inc 668151IG150UL	150 μL

Description

The fidelity of protein synthesis requires efficient discrimination of amino acid substrates by aminoacyl-tRNA synthetases. ArgRS (Arginyl-tRNA synthetase), also known as RARS or DALRD1, belongs to the class-I aminoacyl-tRNA synthetase family that includes the related proteins, LeuRS, ValRS and IleRS. These proteins are large monomeric proteins and play a major role in catalyzing the aminoacylation of tRNA by their cognate amino acid. ArgRS localizes to the cytoplasm and exists as a monomer but can also associate with other tRNA synthetases and auxiliary proteins to form a multisubunit complex. In the presence of ATP, arginine (Arg) and tRNA, ArgRS joins Arg to tRNA(Arg) at its synthetic active site. Two cytoplasmic forms of ArgRS have been described in mammals, differing by the addition of a 73 amino acid sequence that is required for ArgRS assembly into the multisubunit complex.

Specifications

• Antigen: RARS
• Concentration: 1 mg/mL
• Classification: Monoclonal
• Form: Liquid
• Regulatory Status: RUO
• Formulation: PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
• Gene Alias: Arginine tRNA ligase, arginyl tRNA synthetase, ArgRS, DALRD1, RARS
• Gene Symbols: Rars
• Isotype: IgG2b
• Purification Method: Protein A
• Product Type: Antibody

• Clone: 1C8G4
• Applications: Western Blot
• Conjugate: Unconjugated
• Host Species: Mouse
• Target Species: Human, Mouse, Rat
• Gene Accession No.: P40329, P54136, Q9D0I9
• Gene ID (Entrez): 104458, 287191, 5917
• Immunogen: RARS Fusion Protein Ag26399
• Primary or Secondary: Primary
• Content And Storage: -20°C
• Gene: RARS