RARS Mouse anti-Human, Mouse, Rat, Clone: 1C8G4, Proteintech

Catalog No.	Quantity
50-173-7206	150 μL

Catalog No. 50-173-7206 Supplier Proteintech Group Inc Supplier No. 668151IG150UL

Description

Mouse Monoclonal Antibody

The fidelity of protein synthesis requires efficient discrimination of amino acid substrates by aminoacyl-tRNA synthetases. ArgRS (Arginyl-tRNA synthetase), also known as RARS or DALRD1, belongs to the class-I aminoacyl-tRNA synthetase family that includes the related proteins, LeuRS, ValRS and IleRS. These proteins are large monomeric proteins and play a major role in catalyzing the aminoacylation of tRNA by their cognate amino acid. ArgRS localizes to the cytoplasm and exists as a monomer but can also associate with other tRNA synthetases and auxiliary proteins to form a multisubunit complex. In the presence of ATP, arginine (Arg) and tRNA, ArgRS joins Arg to tRNA(Arg) at its synthetic active site. Two cytoplasmic forms of ArgRS have been described in mammals, differing by the addition of a 73 amino acid sequence that is required for ArgRS assembly into the multisubunit complex.

Specifications

• Antigen: RARS
• Applications: Western Blot
• Classification: Monoclonal
• Clone: 1C8G4
• Concentration: 1 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
• Gene: RARS
• Gene Accession No.: P40329, P54136, Q9D0I9
• Gene Alias: Arginine tRNA ligase, arginyl tRNA synthetase, ArgRS, DALRD1, RARS
• Gene Symbols: Rars
• Host Species: Mouse
• Immunogen: RARS Fusion Protein Ag26399
• Purification Method: Protein A
• Quantity: 150 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 104458, 287191, 5917
• Target Species: Human, Mouse, Rat
• Content And Storage: -20°C
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG2b