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RASA2/3 Rabbit anti-Human, Mouse, Polyclonal, Proteintech
SDP

Catalog No. 501735772 Shop All Proteintech Group Inc Products
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Catalog No. 50-173-5772 Supplier Proteintech Group Inc Supplier No. 278351AP150UL
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Rabbit Polyclonal Antibody

The protein encoded by this gene is member of the GAP1 family of GTPase-activating proteins. The gene product stimulates the GTPase activity of normal RAS p21 but not its oncogenic counterpart. Acting as a suppressor of RAS function, the protein enhances the weak intrinsic GTPase activity of RAS proteins resulting in the inactive GDP-bound form of RAS, thereby allowing control of cellular proliferation and differentiation. This family member is an inositol 1, 3, 4, 5-tetrakisphosphate-binding protein, like the closely related RAS p21 protein activator 2. The two family members have distinct pleckstrin-homology domains, with this particular member having a domain consistent with its localization to the plasma membrane.

Specifications

Antigen RASA2/3
Applications Western Blot
Classification Polyclonal
Concentration 0.3 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
Gene RASA2
Gene Accession No. P58069, Q14644, Q15283, Q60790
Gene Alias GAP1(IP4BP), GAP1IP4BP, GAPIII, Ins P4 binding protein, RAS p21 protein activator 3, RASA3
Gene Symbols RASA2, Rasa3
Host Species Rabbit
Immunogen RASA2/3 Fusion Protein Ag27152
Purification Method Antigen Affinity Chromatography
Quantity 150 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 114713, 19414, 22821, 5922
Target Species Human, Mouse
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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