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Apexbio Technology LLC Anti-IL-7Ra/CD127 Antibody (Lusvertikimab) 5mg

Supplier: Apexbio Technology LLC F12165

Lusvertikimab (Anti-IL-7Ra CD127 Antibody CAS 2375835-91-7) is a humanized monoclonal antibody targeting the interleukin-7 receptor alpha chain (IL-7Ra/CD127) It is designed to inhibit IL-7 receptor signaling by preventing heterodimerization of IL-7Ra with the common gamma chain ( c) thereby blocking downstream signaling pathways Lusvertikimab exerts its biological activity primarily by binding IL-7Ra without inducing receptor internalization In studies of B-cell precursor acute lymphoblastic leukemia (BCP-ALL) Lusvertikimab demonstrates inhibitory effects on IL-7-mediated signaling Based on these pharmacological properties Lusvertikimab holds research potential in the study of leukemia biology and the investigation of IL-7 receptor signaling in hematological malignancies
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