RASSF1 Mouse anti-Human, Clone: OTI9F5, lyophilized, TrueMAB™

Catalog No.	Quantity
50-166-1402	100 μg

Catalog No. 50-166-1402 Supplier OriGene Supplier No. CF502510

Description

Mouse Monoclonal Antibody

Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No. 7KMWCO

This gene encodes a protein similar to the RAS effector proteins. Loss or altered expression of this gene has been associated with the pathogenesis of a variety of cancers, which suggests the tumor suppressor function of this gene. The inactivation of this gene was found to be correlated with the hypermethylation of its CpG-island promoter region. The encoded protein was found to interact with DNA repair protein XPA. The protein was also shown to inhibit the accumulation of cyclin D1, and thus induce cell cycle arrest. Seven alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.

Specifications

• Antigen: RASSF1
• Applications: Flow Cytometry, Immunocytochemistry, Immunofluorescence, Western Blot
• Classification: Monoclonal
• Clone: OTI9F5
• Conjugate: Unconjugated
• Formulation: PBS with 8% trehalose and no preservative; pH 7.3
• Gene: RASSF1
• Gene Accession No.: Q9NS23
• Gene Alias: 123F2, NORE2A, RASSF1A, RDA32, REH3P21
• Gene Symbols: RASSF1
• Host Species: Mouse
• Immunogen: Human recombit protein fragment corresponding to amino acids 1-341 of human RASSF1 produced in HEK293T cell.
• Purification Method: Affinity Chromatography
• Quantity: 100 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 11186
• Target Species: Human
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Product Type: Antibody
• Form: Lyophilized
• Isotype: IgG1