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Invitrogen™ RASSF1 Polyclonal Antibody
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Catalog No. PIPA545013
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100 μL
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PIPA545013 100 μL
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Catalog No. PIPA545013 Supplier Invitrogen™ Supplier No. PA545013
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Description

Rabbit Polyclonal Antibody

Peptide sequence: LAGPSDKALS FVLKENDSGE VNWDAFSMPE LHNFLRILQR EEEEHLRQIL Sequence homology: Cow: 100%; Dog: 100%; Guinea Pig: 93%; Horse: 100%; Human: 100%; Mouse: 100%; Pig: 100%; Rabbit: 93%; Rat: 100%; Sheep: 100%; Zebrafish: 85%.

This gene encodes a protein similar to the RAS effector proteins. Loss or altered expression of this gene has been associated with the pathogenesis of a variety of cancers, which suggests the tumor suppressor function of this gene. The inactivation of this gene was found to be correlated with the hypermethylation of its CpG-island promoter region. The encoded protein was found to interact with DNA repair protein XPA. The protein was also shown to inhibit the accumulation of cyclin D1, and thus induce cell cycle arrest. Seven alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.
TRUSTED_SUSTAINABILITY

Specifications

Antigen RASSF1
Applications Western Blot
Classification Polyclonal
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 2% sucrose and 0.09% sodium azide
Gene RASSF1
Gene Accession No. Q9NS23
Gene Alias 123F protein; 123F2; AA536941; AU044980; cardiac-specific ras association domain family 1 protein; NORE2A; pancreas-specific ras association domain family 1 protein; protein 123F2; Ras association (RalGDS/AF-6) domain family 1; Ras association (RalGDS/AF-6) domain family member 1; Ras association domain family 1; Ras association domain family member 1; ras association domain-containing protein 1; Rassf1; Rassf1A; RASSF1A tumor suppressor; Rassf1B; Rassf1C; RDA32; REH3P21; tumor suppressor protein RDA32; wu:fc17f02; WUGSC:H_LUCA12.5; zgc:112224; zgc:92505; zgc:92505 protein
Gene Symbols RASSF1
Host Species Rabbit
Immunogen Synthetic peptide directed towards the C-terminal of human RASSF1 (aa 275-324).
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 11186
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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