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CD184 Rat anti-Mouse, APC-R700, Clone: 2B11/CXCR4, BD

Catalog No. BDB565522 Shop All BD Biosciences Products
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BDB565522 50 μg
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Catalog No. BDB565522 Supplier BD Biosciences Supplier No. 565522

Description

Rat Monoclonal Antibody

The 2B11/CXCR4 monoclonal antibody specifically binds to mouse CD184, which is also known as the C-X-C Chemokine Receptor type 4 , CXCR4. CXCR4 (previously known as Fusin and LESTR), is a seven-transmembrane, G-protein-coupled receptor. It is the specific receptor for the CXC chemokine, SDF-1/CXCL12. Mouse CXCR4 shows 91% homology at the amino acid level with human CXCR4. CXCR4 is widely expressed by hematopoietic and non-hematopoietic cell types including neutrophils, monocytes, T cells, B cells, CD34-positive progenitor cells, endothelial cells, neurons and astrocytes. Human CXCR4 is used by T-tropic HIV-1 as a co-receptor for viral entry. The mouse Cxcr4 gene has been mapped to chromosome 1.

TRUSTED_SUSTAINABILITY

Specifications

Antigen CD184
Applications Flow Cytometry
Classification Monoclonal
Clone 2B11/CXCR4
Concentration 0.2mg/mL
Conjugate APC-R700
Description CXCR4, C-X-C chemokine receptor type 4; Fusin; LESTR; PB-CKR; Sdf1r
Formulation Aqueous buffered solution containing protein stabilizer and ≤0.09% sodium azide.
Host Species Rat
Immunogen GST-NCXCR4 fusion protein
Purification Method Affinity Purified
Quantity 50 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 12767
Target Species Mouse
Content And Storage Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Isotype IgG2b κ
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