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CD49d Rat anti-Mouse, Brilliant Violet 711, Clone: R1-2, BD Optibuild™

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Catalog No. BDB740661 Supplier BD Biosciences Supplier No. 740661
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Description

Rat Monoclonal Antibody

The R1-2 monoclonal antibody specifically binds to α 4 chain (CD49d), which is expressed as a heterdimer with either of two β , β 1 or β 7 (also known as β p). The α 4β α 4β 7 also preferentially binds to the mucosal vascular addressin, MAdCAM-1. The R1-2 antibody blocks some α 4 integrin-mediated binding functions. In combination with mAb 9C10 (MFR4.B) (Cat. No. 553313), binding of VLA-4 expressing cells to VCAM-1 can be almost completely inhibited.

TRUSTED_SUSTAINABILITY

Specifications

Antigen CD49d
Applications Flow Cytometry
Classification Monoclonal
Clone R1-2
Concentration 0.2mg/mL
Conjugate Brilliant Violet 711
Description Integrin α4; Itga4; Integrin alpha-4; LPAM alpha; VLA-4 alpha; VLA-4a
Formulation Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species Rat
Immunogen AKR/Cum mouse spontaneous T lymphoma line TK1
Purification Method Affinity Purified
Quantity 50 μg
Regulatory Status RUO
Primary or Secondary Primary
Target Species Mouse
Content And Storage Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Isotype IgG2b κ
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Safety and Handling

WARNING: Reproductive Harm - www.P65Warnings.ca.gov

For Research Use Only

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