Gibco™ Rat GDNF Recombinant Protein, PeproTech®

E. coli Recombinant Protein

Supplier:  Gibco™ 4505110UG

Catalog No. 450-51-10UG

Description

GDNF is a glycosylated, disulfide-bonded homodimer molecule. It was first discovered as a potent survival factor for midbrain dopaminergic neurons and was then shown to rescue these neurons in animal models of Parkinson's disease. GDNF is about 100 times more efficient survival factor for spinal motor neurons than the neurotrophins. GDNF is a neurotrophic factor that enhances survival and morphological differentiation of dopaminergic neurons and increases their high-affinity dopamine uptake.

Specifications

• Accession Number: Q07731
• Formulation: protein with no preservative
• Molecular Weight (g/mol): 30
• Quantity: 10 μg
• Storage Requirements: -20°C
• Endotoxin Concentration: <1 EU/μg
• Gene Symbol: GDNF
• Conjugate: Unconjugated
• Sequence: MSPDKQAAAL PRRERNRQAA AASPENSRGK GRRGQRGKNR GCVLTAIHLN VTDLGLGYET KEELIFRYCS GSCEAAETMY DKILKNLSRS RRLTSDKVGQ ACCRPVAFDD DLSFLDDSLV YHILRKHSAK RCGCI
• Purity or Quality Grade: ≥ 98% by SDS-PAGE gel and HPLC analyses.

• For Use With (Application): Functional Assay
• Gene ID (Entrez): 25453
• Name: Rat GDNF
• Source: E. coli
• Regulatory Status: RUO
• Gene Alias: AI385739; Astrocyte-derived trophic factor; ATF; ATF1; ATF2; Gdnf; glial cell derived neurotrophic factor; glial cell line derived neurotrophic factor; Glial cell line derived neutrophic factor; glial cell line-derived neurotrophic factor; gndf; HFB1-GDNF; hGDNF; H-GDNF; HSCR3; mGDNF; neurotrophic factor
• Specific Reactivity: Rat
• Recombinant: Recombinant
• Form: Lyophilized