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Proteintech Group Inc Rat IL10 ELISA Kit 96well
SDP

Supplier:  Proteintech Group Inc KE2000396T

Encompass_Preferred

Interleukin 10 is an essential anti-inflammatory cytokine that plays important roles as a negative regulator of immune responses to microbial antigens. IL10 is mainly secreted by macrophages, but also by T helper 1 (Th1) and Th2 lymphocytes, dendritic cells, cytotoxic T cells, B lymphocytes, monocytes and mast cells. It downregulates the expression of Th1 cytokines, MHC class II antigens, and co-stimulatory molecules on macrophages. It also enhances B cell survival, proliferation, and antibody production. IL10 can block NF-κB activity, and is involved in the regulation of the JAK-STAT signaling pathway. IL10 activity is mediated by the IL10 receptor (IL10R) which is a member of the class II cytokine receptor family.

Catalog No. 50-197-4175


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