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Invitrogen™ Rat OPN ELISA Kit
ELISA
$700.00 - $3290.00
Specifications
| Accession Number | 2 AR; 2b7; 44 kDa bone phosphoprotein; Apl-1; BNSP; Bone sialoprotein 1; Bsp; BSPI; calcium oxalate crystal growth inhibitor protein; early T-lymphocyte activation 1; Early T-lymphocyte activation 1 protein; Eta; ETA-1; HGNC:11255; MGC110940; Minopontin; nephropontin; Op; Opn; Opnl; OSP; Osteopontin; osteopontin/immunoglobulin alpha 1 heavy chain constant region fusion protein; osteopontin-like protein; PSEC0156; Ric; Secreted phosphoprotein 1; secreted phosphoprotein 1 (osteopontin, bone sialoprotein I, early T-lymphocyte activation 1); secreted phosphoprotein 1 variant 6; Sialoprotein (osteopontin); Spp1; SPP-1; SPP1/CALPHA1 fusion; unnamed protein product; urinar; urinary stone protein; Uropontin |
|---|---|
| Assay Range | 80 to 20,000 pg/mL |
| Assay Sensitivity | 80 pg/mL |
| Conjugate | HRP |
| Product Type | ELISA |
Description
Rat OPN quantitates rat OPN in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant rat OPN.
Osteopontin is an arginine-glycine-aspartic acid (RGD)-containing glycoprotein that interacts with integrins and CD44 as major receptors. It is a multifunctional protein involved in bone mineralization, cell adhesion, cell migration, chronic inflammatory disease and transformation. Proteolytic cleavage by thrombin and matrix metalloproteinases close to the integrin-binding Arg-Gly-Asp sequence modulates the function of OPN and its integrin binding properties. Thrombin-cleaved fragments of Osteopontin are overexpressed in malignant glial tumors and provide a molecular niche with survival advantage and provide a novel substrate for plasmin and cathepsin D.Specifications
| 2 AR; 2b7; 44 kDa bone phosphoprotein; Apl-1; BNSP; Bone sialoprotein 1; Bsp; BSPI; calcium oxalate crystal growth inhibitor protein; early T-lymphocyte activation 1; Early T-lymphocyte activation 1 protein; Eta; ETA-1; HGNC:11255; MGC110940; Minopontin; nephropontin; Op; Opn; Opnl; OSP; Osteopontin; osteopontin/immunoglobulin alpha 1 heavy chain constant region fusion protein; osteopontin-like protein; PSEC0156; Ric; Secreted phosphoprotein 1; secreted phosphoprotein 1 (osteopontin, bone sialoprotein I, early T-lymphocyte activation 1); secreted phosphoprotein 1 variant 6; Sialoprotein (osteopontin); Spp1; SPP-1; SPP1/CALPHA1 fusion; unnamed protein product; urinar; urinary stone protein; Uropontin | |
| 80 pg/mL | |
| ELISA | |
| Colorimetric Microplate Reader | |
| SPP1 | |
| <10 | |
| HRP | |
| Plasma 50 μL, Serum 50 μL, Supernatant 50 μL | |
| Osteopontin | |
| 4 hrs 45 mins |
| 80 to 20,000 pg/mL | |
| HRP | |
| Plasma, Serum, Supernatant | |
| 25353 | |
| <12% | |
| Pre-coated 96 well plate, Standard, Assay Diluent concentrate, Biotinylated Detection Antibody, SAV-HRP, Wash Buffer, Chromogen, Stop Solution, Adhesive Plate Covers | |
| RUO | |
| 2°C to 8°C | |
| 1 hrs 20 mins |
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