Invitrogen™ Rat VAMP2 (aa 1-18) Synthetic Peptide

Catalog No.	Quantity
PEP101	50 μg

Catalog No. PEP101 Supplier Invitrogen™ Supplier No. PEP101

Description

Synthetic Peptide

Rat VAMP-2 (residues 1-18) Synthetic Peptide, PEP-101, from Invitrogen.

The vesicle associated membrane proteins (VAMP) or synaptobrevins are calcium binding proteins specific to eukaryotes. VAMPs, along with synaptosomal associated protein of 25 kDa (SNAP-25) and syntaxin, form the core complex of soluble NSF attachment protein receptor (SNARE) proteins that interact with the soluble proteins N-ethylmaleimide-sensitive factor (NSF) and alpha-SNAP. These membrane associated proteins play a key role in the regulation of vesicle membrane fusion with the plasma membrane. The Clostridium tetani neurotoxin is a metalloprotease with specificity for VAMP. In Alzheimer's disease, VAMP levels of all isoforms appear to be significantly lowered. It is suggested that VAMP-2 is a resident protein of the insulin-sensitive glucose transporter type 4 (GLUT4) compartment and that it is required for GLUT4 vesicle incorporation into the cell surface in response to insulin.

Specifications

• Gene ID (Entrez): 24803
• Species: Rat
• Purification Method: purified
• Accession Number: P63045
• Common Name: Rat VAMP2 (aa 1-18)
• Concentration: 0.5 mg/mL
• Content And Storage: -20°C. Avoid freeze-thaw cycles.
• Description: Synthetic Peptide
• Format: Lyophilized
• Formulation: peptide with no preservative
• For Use With (Application): Control
• Gene Symbol: Vamp2
• Lyophilized: Lyophilized
• Preservative: No preservative
• Product Type: Peptide
• Quantity: 50 μg
• Regulatory Status: RUO - research use only
• Sequence: M(1)-S-A-T-A-A-T-V-P-P-A-A-P-A-G-E-G-G(18)

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov