RB1 Mouse anti-Human, Clone: OTI1B1, lyophilized, TrueMAB™

Catalog No.	Quantity
50-166-7526	100 μg

Catalog No. 50-166-7526 Supplier OriGene Supplier No. CF805657

Description

Mouse Monoclonal Antibody

Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No. 7KMWCO

Rb is a tumor suppressor nuclear phosphoprotein capable of binding to DNA. It is phosphorylated on serine and threonine, but not on tyrosine residues. It forms a complex with SV40 large T antigen, adenovirus E1A, and human papilloma virus-16 E. Rb protein may act by regulating transcription and loss of its function leads to uncontrolled cell growth. Aberrations in the RB gene have been implicated in cancers of breast, colon, prostate, kidney, nasopharynx, and leukemia.

Specifications

• Antigen: RB1
• Applications: Western Blot
• Classification: Monoclonal
• Clone: OTI1B1
• Conjugate: Unconjugated
• Formulation: PBS with 8% trehalose and no preservative; pH 7.3
• Gene: RB1
• Gene Accession No.: P06400
• Gene Alias: OSRC, PPP1R130, RB, p105-Rb, pRb, pp110
• Gene Symbols: RB1
• Host Species: Mouse
• Immunogen: Human recombit protein fragment corresponding to amino acids 309-590 of human RB1 produced in E.coli.
• Purification Method: Affinity Chromatography
• Quantity: 100 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 5925
• Target Species: Human
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Product Type: Antibody
• Form: Lyophilized
• Isotype: IgG1